Bioactive effects of saturated colloidal ionic dispersions on yeast samples, moulds and topical infections in animals and humans are unmistakably more apparent compared to bioactive effects of lower saturation dispersions, i.e. the same level of efficiency can be achieved with less volume of the dispersion.
Is Colloidal Silver Good for Wounds?
Recently we have tested the effectiveness of saturated ionic silver dispersion (containing a high amount of silver ions) in the facilitation of open wound healing process. In a recent accident, a portion of skin and the underlying tissue of a palm was torn off, and we were presented with an exciting opportunity to test the efficiency of highly concentrated colloidal silver dispersion in improving the wound healing process. It was decided to forego any regular medical treatment whatsoever in order to determine whether saturated colloidal ionic silver dispersion is a viable alternative to conventional medical therapies for open wounds. The only two other treatments that were applied on the wound were initial irrigation of the wound with nascent oxygen during removal of remaining debris from wound and later electrotherapy treatment of painful wrist and thumb joints. Other than those two exceptions, the wound was treated solely with highly concentrated colloidal ionic silver dispersion. We took a few photographs to document different phases of silver cations (Ag+) facilitating the wound healing process.
The accident caused significant damage to the skin and has entirely stripped away epidermis and most of the dermis. Initially, the wound was contaminated with debris remaining from the accident, and it had to be cleared and disinfected as soon as possible to prevent the possible development of an infection. Disinfection of the wound during the initial process of cleaning was done by irrigation with nascent oxygen. In this case, we chose nascent oxygen for initial treatment due to its higher activity and ability to penetrate layers of living tissue cells which is something that colloidal ionic silver dispersion is incapable of doing. Although rather efficient in the disinfection of open wounds, nascent oxygen in the past proved itself to be overly aggressive during more extended periods of the wound healing process, causing somewhat unpleasant sensations and effectively slowing down the healing process. After initial cleaning of the wound and disinfection with nascent oxygen, it was once again irrigated with sterile water for injections. Such a precautionary act was done in order to prevent reaction between colloidal ionic silver and salts and minerals remaining from nascent oxygen treatment. If such a reaction occurred, it would have resulted in the synthesis of silver salts which have no useful bioactive properties and have a tendency to accumulate in the wound. Finally, multi-layered sterile gauze soaked with saturated colloidal ionic silver dispersion was placed directly on the wound and secured with adhesive bandage. By maintaining a high concentration of silver cations (Ag+) on the surface of wound aseptic conditions are maintained at all times thus preventing any possible development of infection. What is even more important is the property of silver cations (Ag+) to dedifferentiate red blood cells into polypotent (stem) cells. Several research studies indicate that silver cations (Ag+) exhibit property of being able to dedifferentiate red blood cells into a sort of stem cells which can significantly help the forming of new tissues. In order to exploit such property of silver ions, we found it necessary to keep their high concentration in contact with leaking blood at all times and wet gauze proved to be most beneficial in that regard. Aside from the damaged skin, wrist joint also suffered trauma and subsequent swelling and pain which were at a later stage successfully treated by some of our own electrotherapy devices.
Less than 24 hours after the accident any significant leaking of blood, lymph and plasma from wound stopped. New tissue already started to form. However, such fast rate of new tissue growth presented a bit of problem due to the formation of thicker layers of less flexible new tissue which prevented normal stretching and flexing of hand. The problem was already addressed by continually soaking the gauze with fresh, saturated colloidal ionic silver dispersion, which kept a high level of hydration of the newly formed tissue. Several research studies indicate that silver ions (Ag+) when in direct contact with blood, have the capability of inducing dedifferentiation of red blood cells into a kind of polypotent cells that behave virtually identical to stem cells. It is this bioactive effect of silver ions that is most probably responsible for accelerated healing of wound which at this point became quite observable.
Newly formed tissue already virtually covered the entire wound. At this point, direct contact of the wound with the blunt metal instrument still produced a sensation of pain but to a much lesser degree. The flexibility of newly formed tissue was maintained by continuously moisturising of the wound with highly concentrated colloidal ionic silver dispersion and by skin stretching exercises.
Signs of accelerated tissue healing were still present due to the constant soaking of the wound with saturated colloidal ionic silver. However, at this point, it became obvious that as the residual leaking of blood and plasma subsided, acceleration of wound healing was becoming somewhat less pronounced. Such deceleration of wound healing process would be consistent with fewer amounts of stem cells produced due to less amount of blood coming into contact with silver ions. A thin newly formed layer of dermis almost entirely covered the wound. Outer edges of the wound already started forming a new layer of the epidermis. A sensation of pain when the wound was in contact with a blunt metal instrument was still present, but it was a fraction of the original levels of pain experienced during the first 24 hours after the accident.
Further deceleration of the wound healing process could be observed. As it can be seen in the picture, newly formed dermis and epidermis were partially stripped away during removal of gauze. It must be noted though that pain sensation has almost entirely subsided before mishap with the removal of the gauze. I suspect that deceleration of the healing process is also partially resulting from the lack of colloidal ionic silver penetrative capability. Furthermore, virtually no more polypotent (stem) cells were produced due to lack of direct contact of silver cations (Ag+) with red blood cells.
The normalisation of the healing process rate became rather evident. It became evident that prolonged exposure of the wound to colloidal ionic silver was becoming less effective with no more residual blood leaks present. Perhaps the wound healing rate follows the exponential curve during initial stages of treatment with silver ions due to a large number of red blood cells which are available for the dedifferentiation process to take place. As the residual bleeding and leaking of plasma gradually subside, the curve describing the healing rate in the time domain would gradually fall back to average healing rate.
Two weeks after the accident and start of treatment with saturated colloidal ionic silver dispersion, the wound was almost entirely healed. While it still looked rough, the pain sensation was entirely gone, and the flexibility of the newly formed skin layers returned to normal. We decided to discontinue the treatment as there was no more need for maintenance of the highly aseptic environment. It also became quite apparent that healing process returned to its normal rate of progress due to lack of available layer of blood necessary for stem cell production in the wound.
The wound has completely healed, and there was virtually no scarring present.
Conventional medical treatments such as antiseptics, antibiotics, analgesics or even corticosteroids were not used. Aside from initial irrigation of the wound with nascent oxygen and later electrotherapy treatment of painful wrist and thumb joints, the only thing that facilitated wound healing process was saturated colloidal ionic silver dispersion with a high content of silver cations (Ag+). This case is only a single (partially) documented case where highly concentrated colloidal ionic silver dispersion exhibited its beneficial properties in facilitating the wound healing process, and the single case is statistically insignificant. Still, different observed phases of wound healing process fit results of research studies which indicate that dedifferentiation of red blood cells indeed takes place and is most beneficial in the wound healing process.